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Rotary-Type Aerosol Filling Machine

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20mm Automatic MDI Filling Machine & Metered Dose Inhaler Filling Line

Automatic MDI Aerosol Machine (AL-ZP-MDI) – Rotary Indexing Monoblock for Precision Small-Dose Inhalers & Micro-Sprays. Pure Pneumatic Operation with Integrated Liquid Filling, Valve Crimping & Gas Charging.

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KEY SPECIFICATIONS

● Production Capacity: 1,000 – 1,200 BPH (Continuous Indexing Output)

● Applicable Valve Size: 1/2-Inch (Specialized for MDI & Asthma Inhalers)

● Liquid Filling Capacity: Max. 15 ml (Precision Micro-Dosing ≤ ±0.5g)

● Compatible Propellants: Medical R134a / HFA, High-Purity N₂, Butane, Propane, Freon

● Sanitary Standard: SUS316L Contact Parts (Complies with Pharmaceutical GMP Standards)

  • Description
  • Product Paramenters
  • Technical Guide & Buyer RFQ
  • FAQ: Common Questions

Product Overview & Engineering Architecture

The AILE AL-ZP-MDI Rotary Aerosol Machine is an engineered rotary monoblock system specifically designed for small-dose pharmaceuticals and precision cosmetics with a volume under 60ml, particularly tailored for metered dose inhalers (MDIs) and 1/2-inch miniature valves.

Built on a pure pneumatic architecture, the machine operates completely without electrical power, eliminating explosion hazards when charging flammable propellants or medical aerosols. It seamlessly coordinates micro-liquid dosing, airtight valve crimping, and pressurized propellant charging on an integrated rotary indexing platform.

All fluid-contact components are manufactured from sanitary SUS316L stainless steel, ensuring rigorous compliance with pharmaceutical GMP production requirements for sterile and contamination-free formulation delivery.

AL-ZP-MDI Automatic Rotary MDI Aerosol Filling Machine

Step-by-Step MDI Production Sequence

  1. Star-Wheel Indexing: Compact aerosol cans (Φ22–28mm, H: 45–150mm) enter the precision rotary puck star wheel for accurate station positioning.
  2. Micro-Dose Liquid Dosing: High-precision SUS316L volumetric piston dosing injects active liquid (up to 15ml) with strict accuracy within ±0.5g.
  3. 1/2-Inch Valve Crimping: High-rigidity expanding collet heads seal the miniature 1/2" valve cup onto the can mouth, ensuring hermetic seal integrity.
  4. High-Pressure Propellant Charging: Propellants such as medical-grade R134a, nitrogen (N₂), butane, or Freon (up to 25ml) are charged through the valve stem under 0.6–0.8 MPa working pressure.
  5. Buffer Slide Discharge: Fully sealed and pressurized inhaler cans are guided smoothly along the discharge slideway directly into collection trays for downstream checkweighing.
Technical Parameter Design Specification / Confirmed Data
Machine Model AL-ZP-MDI (Rotary Type)
Production Capacity 1,000 – 1,200 BPH (Cans/Hour)
Max. Liquid Filling Volume 15 ml (Specialized for micro-dosing ≤ 60ml)
Max. Gas Filling Volume 25 ml
Filling Accuracy ≤ ±0.5 g
Suitable Aerosol Can Diameter Φ22 – Φ28 mm
Suitable Aerosol Can Height 45 – 150 mm
Suitable Aerosol Valve Size 1/2" (Miniature Inhaler & MDI Valve)
Applicable Propellants Propane, Butane, Freon, N&sub2;, R134a, etc.
Working Air Pressure 0.6 – 0.8 MPa
Maximum Air Consumption 1.6 m³/min
Drive System & Safety 100% Pure Pneumatic Operation (No electrical power supply needed)
Primary Construction Materials Main Frame: SUS304 | Fluid Contact Parts: Sanitary SUS316L (GMP Standard)
Machine Dimensions (Net) 910 × 910 × 1600 mm
Machine Net Weight 335 kg

Why Dedicated 1/2-Inch Tooling Matters for Micro-Aerosols

Standard commercial aerosols rely on 1-inch (25.4mm) aperture valves for large can openings. In contrast, Metered Dose Inhalers (MDIs) and micro-dosing sprays utilize miniature 1/2-inch (approx. 13mm) valves on narrow aluminum or tinplate cans (Φ22–28mm) for targeted pulmonary, nasal, or oral administration.

Standard filling lines cannot crimp or gas miniature 1/2" containers without crushed necks or valve stem leakage. The AILE AL-ZP-MDI rotary platform provides custom star-wheel pocket indexing, miniature expanding crimping collets, and ultra-fine SUS316L volumetric metering designed specifically for small-batch pharmaceutical and laboratory aerosol production.

Engineering Feature AL-ZP-MDI Rotary Aerosol Machine Standard 1-Inch Aerosol Machine
Applicable Valve Size 1/2" (Micro-Valve for Inhalers) 1 inch (25.4 mm) Standard Valve
Dosing Capacity Range Max. 15 ml liquid | Max. 25 ml gas 20 ml – 500 ml+ high-volume filling
Applicable Container Size Φ22–28 mm | Height: 45–150 mm Φ35–65 mm | Height: 80–300 mm
Power & Drive System 100% Pure Pneumatic (No electricity) Electro-pneumatic / Motor driven
Sanitary Standard SUS316L product contact (GMP compliant) Standard SUS304 / Industrial grade

*For detailed background on medical propellants, safety zoning, and gassing mechanics, read our technical overview: What Is HFA-134a? MDI Propellant & Filling Process.

Technical Information to Confirm Before Machine Ordering

Because miniature 1/2" valves, crimping depths, and propellant pressures vary across pharmaceutical and cosmetic formulations, AILE custom-machines star-wheel pockets and crimp tooling to your exact packaging specs. Please confirm:

  • Can Dimensions: Outer diameter (Φ22–28mm) and total container height (45–150mm).
  • Valve Specifications: 1/2" continuous or metered dose valve technical drawings.
  • Target Dosage: Liquid dosing volume (up to 15ml) and target gas charge volume (up to 25ml).
  • Propellant Choice: Medical R134a, N&sub2;, butane, propane, or Freon blends.
  • Testing Samples: Please provide 20–30 physical empty cans and matching 1/2" valves to AILE for tooling testing before factory shipment.

Need a Quotation or Tooling Evaluation for AL-ZP-MDI?

Send our engineers your container dimensions, valve drawings, and target production volume for a customized quotation and engineering layout drawing.

Request Quotation & Technical Consultation

Frequently Asked Questions About AL-ZP-MDI

What is an MDI aerosol filling machine, and how does it work?

An MDI (Metered Dose Inhaler) filling machine is a specialized packaging system engineered for pharmaceuticals and micro-dose sprays under 60ml. Operating on an indexing rotary star wheel, the machine coordinates three core operations: micro-volume liquid dosing, high-precision valve crimping, and through-the-valve propellant charging in an enclosed, pure pneumatic workstation.

What valve and can sizes are compatible with the AL-ZP-MDI?

The standard AL-ZP-MDI is configured for 1/2-inch (approx. 13mm) miniature aerosol valves and compact aerosol cans with diameters between Φ22 mm and Φ28 mm and heights between 45 mm and 150 mm. Customized pucks and crimping heads can also be machined for project-specific container geometries.

Does this machine require electrical power, and is it explosion-proof?

No electrical power supply is required. The AL-ZP-MDI features a 100% pure pneumatic control architecture driven solely by compressed air (0.6–0.8 MPa). Because there are no electrical components, motors, or switches, it completely eliminates electrical spark hazards when handling flammable propellants (such as butane, propane, or LPG) or volatile medical solvents.

What are the maximum filling volumes and dosing accuracy?

The machine delivers a maximum liquid dosing volume of 15 ml and a maximum gas charging volume of 25 ml, with an accuracy within ≤ ±0.5 g. It is purpose-built for high-precision micro-dosing applications such as asthma inhalers, throat sprays, and targeted medical mists.

Which propellants can be filled through the valve?

The high-pressure gas filling head supports a wide variety of propellants, including medical-grade R134a / HFA-134a, nitrogen (N₂), Freon blends, butane, and propane. The booster pump maintains stable charging pressure regardless of gas supply fluctuations.

Does the machine meet pharmaceutical GMP sanitary standards?

Yes. All liquid-contact parts (including metering cylinders, fluid pipelines, and dosing nozzles) are manufactured from sanitary SUS316L stainless steel with fine mirror polishing. The machine frame is built in durable SUS304, meeting pharmaceutical cleanroom and GMP manufacturing compliance.

Should I provide can and valve samples before ordering?

Yes, physical samples are strongly recommended. Because miniature 1/2-inch valves, crimping depths, and can profiles vary across manufacturers, providing 20 to 30 empty cans and valve samples ensures AILE engineers custom-machine star-wheel pockets, crimping collets, and gas nozzles to your exact packaging dimensions prior to factory testing.

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